Covid Vaccine - Temporarily locked

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  • Tammygirl
    Tammygirl Club Member Posts: 7,957 ✭✭✭
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    edited November 2020 #92

    Question, if when the vaccine comes out and we are lucky enough to be given the 2 doses 3 weeks apart. If we were then to take a test would it come back positive?

    The reason I ask is that certain countries where we are free to travel to without restrictions require that you have a 'certificate to travel'  this means a test 72 hours prior to your flight. If you have recently had the vaccine could this give a positive result?  

    I'm not sure if the answers are yet know to this question (and many more) but its something that would have to be known if we want to get back to taking holidays and travelling.

  • Tinwheeler
    Tinwheeler Forum Participant Posts: 23,135 ✭✭✭
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    edited November 2020 #93

    It's my understanding that the vaccine does not give you the infection but enables the body to produce anti-bodies to the disease.

    An anti-body test would show your immunity but this is different from the antigen test which shows active infection. It is the antigen test that is routinely used to detect current infection.

    I've had all the usual inoculations but I’d not test positive for smallpox, TB, polio and so on.

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #94

    I don't know but I suspect that it will depend on how the one you receive works.  

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #95

    Most of the candidate are RNA vaccines.  This paper may throw some light on the process and its effect.

    rna-vaccines

  • Tammygirl
    Tammygirl Club Member Posts: 7,957 ✭✭✭
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    edited November 2020 #96

    Thanks for your comments. I guess it will depend on which vaccine is received as they may work differently. 

    I wondered as if you contract covid then for awhile you are infectious,  once you are no longer infectious, a test can still show that you are positive as it hangs around in your system for weeks.

    I've had all the usual inoculations but I’d not test positive for smallpox, TB, polio and so on.

    So have I,  would I test positive for any of them, well no not now but could I have in the days post vaccine. I remember getting the smallpox one I had a very severe reaction.

  • Tammygirl
    Tammygirl Club Member Posts: 7,957 ✭✭✭
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    edited November 2020 #97

    Thanks for that most informative.smile

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #98

    As I understand it if you were tested for anything that you have been innoculated against you should test positive for antibodies but not the disease per se.  TB may be an exception to that. 

  • ABM
    ABM Forum Participant Posts: 14,578
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    edited November 2020 #99

     Hmm,  undecided, wonder if I would still test positive for Ind Coop and/or Greenall Whitley  ?

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #100

    Possibly, but there is a cure ... start drinking decent beers winklaughing

  • redface
    redface Forum Participant Posts: 1,701
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    edited November 2020 #101

    Didn't Matt Hancock say during the Brexit debate that he had purchased loads of refrigeration to mitigate the concerns of storing the likes of insulin if there were supply problems 

    No David - he was conned by a second hand fridge/freezer salesman and didn't realise that such machines do not chill down to the required -80 deg. or so that is required. laughing

     

  • Whittakerr
    Whittakerr Club Member Posts: 3,472 ✭✭✭✭
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    edited November 2020 #102

    More good news. I've just seen on the BBC website an American company have just announced they have a vaccine with a 95% success rate.

    Still plenty of unanswered questions, and as yet, the UK haven't placed   a firm order for this particular vaccine, but it seems that there will be several different vaccines available in the new year.

  • brue
    brue Forum Participant Posts: 21,176 ✭✭✭✭✭
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    edited November 2020 #103

    Yes, the vaccine news is becoming more encouraging. The Smallpox vaccine is 95% effective and has eliminated the disease so a 95% result for Covid trials sounds good! I see Janssen are also seeking vaccine volunteers LINK

  • Freddy55
    Freddy55 Club Member Posts: 1,809 ✭✭✭✭
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    edited November 2020 #104

    I could be wrong, but I understand that it’s not known whether or not a vaccine will actually stop one catching and spreading the virus. If the vaccine doesn’t stop the spread, giving it to the young first, for example,  would imo be a waste of vaccine.

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #105

    They may well stop you developing symptoms and becoming ill but it would appear that they don't yet know whether or not you can still become a carrier and if so for how long.  I expect that in due course we will find out.  

  • EasyT
    EasyT Forum Participant Posts: 16,194
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    edited November 2020 #106

    We have no reason to suspect it won't stop catching and transmitting. Presumably the only way that its producers could say that it is affective is by no evidence of infection

  • Freddy55
    Freddy55 Club Member Posts: 1,809 ✭✭✭✭
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    edited November 2020 #107

    The only thing I’m presuming is that it will/should stop one becoming ill. My understanding is that even with a vaccine, the virus will be with us for many (?) years.

  • nelliethehooker
    nelliethehooker Club Member Posts: 13,636
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    edited November 2020 #108

    Matt Hancock confirmed tonight that they have an order for 5 million doses of the latest vaccine, which brings the total of vaccine doses on order to 355 million.

  • ABM
    ABM Forum Participant Posts: 14,578
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    edited November 2020 #109

    ??  undecided  Wonder if that load will help protect all those mink undecided ?? 

  • Compo
    Compo Forum Participant Posts: 324
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    edited November 2020 #110

    Good news about the Astrazeneca vaccine. Seems strange to me that it was only by making an error with the dosage that it was found to work better. Lets hope they don't make any more errors  when they are using it.

  • Rocky 2 buckets
    Rocky 2 buckets Forum Participant Posts: 7,101
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    edited November 2020 #111

    No errors C, that’s fake news🤷🏻‍♂️☹️. The dosage criteria & amounts are always checked in the different ratios for efficacy. Under this level of creation & importance no mistakes are made they are all under a microscope & examined to destruction. It’s falsehoods like your statement that actually costs lives. When I first heard that rumour I researched it thoroughly & found nothing to back it up. These Labs are world class from every major world power(except Russia) they don’t make mistakes serendipity plays no part.

  • Compo
    Compo Forum Participant Posts: 324
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    edited November 2020 #112

    Thanks for putting me right R2b. That will teach me for reading the daily mail.

  • Rocky 2 buckets
    Rocky 2 buckets Forum Participant Posts: 7,101
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    edited November 2020 #113

    It truly is better to check known & trusted sources. All the tabloids at some point have been sued by aggrieved people & companies due to tabloid stories & their falsehoods. Reputations are nothing compared to lives.

  • Compo
    Compo Forum Participant Posts: 324
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    edited November 2020 #114

    Thanks for the advice R2b. I did say I found it strange but I must admit I didn't check it with any other source. Did you find from your research why the vice president from Astrazenca was reported to have told Journalists that that was how it was discovered, or was that a lie as well. If it was I can see more libel claims being made.

  • JVB66
    JVB66 Forum Participant Posts: 22,892
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    edited November 2020 #115

    It sounds more like Guardian type newssurprised

    As was advised by the Oxford scientists it was found that two different size of dose ,had better results than two of the same larger dose

  • Compo
    Compo Forum Participant Posts: 324
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    edited November 2020 #116

    I think, but I haven't checked with any other source, that it was reported in there as well.

  • DEBSC
    DEBSC Forum Participant Posts: 1,362
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    edited November 2020 #117

    What I don't understand is why they said it was 62 to 70per cent effective and then an hour later that it was 90 per cent by giving half a dose on the first vaccine. If they can save on vaccine and get a better rate it seems obvious that they will use the second option, so why release the news of the lower figure first? Either way they are amazing people, they must have worked so hard and are so clever. All credit and our great thanks to them.

  • SteveL
    SteveL Club Member Posts: 12,302 ✭✭✭
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    edited November 2020 #118

    Certainly reported as such in today's Telegraph, along with the fact AZ's Vice President said it was so. If they've all got it wrong there are going to be a few apologies forthcoming.

  • Unknown
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    edited November 2020 #119
    The user and all related content has been Deleted User
  • DavidKlyne
    DavidKlyne Club Member Posts: 13,857 ✭✭✭
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    edited November 2020 #120

    I think we should give it the full name, it's the Oxford AstraZeneca vaccine, jointly developed between Oxford University and AstraZeneca. They don't fully understand why giving a smaller initial dose and then a second larger dose works better but they think the original smaller dose actual helps prime the immune system according to Prof Sarah Gilbert from the University of Oxford. You can read about it here in the Guardian. The serious papers tend to relay the information in a more serious way than perhaps the tabloids tend to do?

  • LLM
    LLM Forum Participant Posts: 1,555 ✭✭
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    edited November 2020 #121

    These Labs are world class from every major world power (except Russia) they don’t make mistakes serendipity plays no part.

    If only that was true.  Over the years hundreds of drugs, including vaccines, have been found to cause harm and be ineffective.  I'm not suggesting that there is anything wrong with these new CV19 vaccines but only time will tell.