Recommended route to Strasbourg

hitchglitch
hitchglitch Forum Participant Posts: 3,007
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On our way to Italy (via Basel and Locarno) we always like to stay at the excellent municipal site in Obernai near Strasbourg. Generally we go from Calais via Reims but I believe it is just as quick to go through Belgium and avoid tolls. Can anybody recommend
a route and a possible stop-over say 3 to 4 hours from Calais?

Alternatively, is there an attractive route through Germany to Lake Maggiore?